If left untreated, jaundice can cause a condition called kernicterus, which can cause brain damage, deafness, mental retardation and cerebral palsy.    From Wordnik.com.  [msnbc.com: Top msnbc.com headlines] Reference

The kernicterus affected every muscle in Lexi's body.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Gourley GR (1997) Bilirubin metabolism and kernicterus.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Very high bilirubin levels can cause kernicterus, a type of brain damage.    From Wordnik.com.  [IdahoStatesman.com News Updates] Reference

Toxic levels of bilirubin can cause severe neurological damage called kernicterus.    From Wordnik.com.  [Health News from Medical News Today] Reference

The incidence of kernicterus ranges from 0.4 to 2.9 per 100,000 live births, according to previous research.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

And like Blue, a 4-year-old boy from Fayetteville, N.C., whose kernicterus is so severe he is fed through a tube.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Ahdab-Barmada M, Moossy J (1984) The neuropathology of kernicterus in the premature neonate: diagnostic problems.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Death or serious disability (kernicterus) associated with failure to identify and treat hyperbilirubinemia in neonates.    From Wordnik.com. Reference

Based on how Lexi does, neurologist Kathryn Holloway said they may consider deep brain stimulation for other children with kernicterus.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Although the majority of neonatal jaundice is benign, some neonates with severe hyperbilirubinemia develop bilirubin encephalopathy or kernicterus.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"We are seeing encouraging signs," said Dr. Steven Shapiro, a kernicterus expert at Virginia Commonwealth University Medical Center in Richmond, where Lexi had surgery.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

"Lexi has given us the first realm of excitement," said Vicki Dornbos of Spokane, Wash., whose 5-year-old son, Zachary, has the same type of brain damage, called kernicterus.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

It is evident that jaundiced neonates have total serum bilirubin concentrations of 7 to 17 mg/dL and serum bilirubin concentrations higher than 20 mg/dL may cause kernicterus.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The core clinical features of UCB encephalopathy may range from mild mental retardation and subtle cognitive disturbances to deafness and severe cerebral palsy, seizure or death from kernicterus.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"Perhaps partly because I have served as an expert consultant on dozens of heartbreaking kernicterus legal cases, I find the argument in favor of universal bilirubin screening and systematic follow-up persuasive," he wrote.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

Some newborns, however, especially preterm infants with hemolytic diseases, the concentration of UCB may rise to higher levels that cause bilirubin encephalopathy or may progress to kernicterus resulting in severe neurological dysfunctions.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference