With their modification, which they call the lysosome patch clamp, Xu's group was able to record TRPML1 activity in the tiny lysosome.    From Wordnik.com.  [Media Newswire] Reference

The enzyme functions in a part of the cell called the lysosome, where cellular components are broken down, or metabolized, for recycling.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

They led to the discovery of a new cell part, the lysosome, which received its name in.    From Wordnik.com.  [Christian de Duve - Autobiography] Reference

Biological waste material normally is broken down by the part of the cell known as the lysosome.    From Wordnik.com.  [Key to Alzheimer's: Waste in Cells] Reference

Researchers are trying different approaches to target the lysosome as a possible treatment for Alzheimer's and other diseases.    From Wordnik.com.  [Key to Alzheimer's: Waste in Cells] Reference

Likewise, a type of cell organelle, the lysosome, in which proteins absorbed from outside are broken down, had long been studied.    From Wordnik.com.  [The Nobel Prize in Chemistry 2004 - Information for the Public] Reference

As your referenced post says, it DOES make more sense not to generate them in the first place, and to use ketosis as a lysosome-cleaner.    From Wordnik.com.  [Vegetarians AGE faster | The Blog of Michael R. Eades, M.D.] Reference

LDL In the lysosome, lipids are deseterified are hydrolyzed 19.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Our data suggest that inhibition of lysosome-PM fusion-dependent redistribution of.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Then the lysosome doesn't work and things build up in cells that shouldn't be there.    From Wordnik.com.  [Scientific American] Reference

Communications, focused on gateways called calcium channels in the lysosome membrane.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

This happens even before the lysosome "swallows" the vesicle and digests its contents.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

But they manage to bypass the lysosome, where other pathogens would normally be destroyed.    From Wordnik.com.  [Infection Control Today Site Wide Content Feed] Reference

Transfected cells were treated with proteasome and lysosome inhibitors as described above.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Nature Communications, focused on gateways called calcium channels in the lysosome membrane.    From Wordnik.com.  [Newswise: Latest News] Reference

Walkley SU (2007) Pathogenic mechanisms in lysosomal disease: a reappraisal of the role of the lysosome.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The PS1 gene activates lysosome enzymes that digest waste proteins during a process called autophagy.    From Wordnik.com.  [Kansas City infoZine Headlines] Reference

What do a vacuole, a centriole, a lysosome, an endoplasmic reticulum and a Golgi apparatus have in common?.    From Wordnik.com.  [SFGate: Top News Stories] Reference

The autophagosome fuses with the lytic lysosome to form autophagolysosomes that degrades engulfed molecules.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

If antigen dissociates from the antibody while in the endosome it is shunted to the lysosome for degradation.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

SifA recruits membranes enriched in lysosome associated membrane protein 1 (LAMP1) and is needed for growth of.    From Wordnik.com.  [Proceedings of the National Academy of Sciences current issue] Reference

This study shows that variants of proteins that guide hydrolases to the lysosome are associated with stuttering.    From Wordnik.com.  [Clinical Cases and Images: CasesBlog] Reference

The cell carries the vesicle to a lysosome, which virtually serves as its digestive tract with numerous enzymes.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

The latter pathway would predominate in older patients because proteasome and lysosome function declines with age.    From Wordnik.com.  [Health News from Medical News Today] Reference

"If we can somehow manipulate the lysosome iron level, we probably can provide a treatment for the patient," Xu said.    From Wordnik.com.  [innovations-report] Reference

The high glucose-induced reduction in GLUT-1 protein in normal chondrocytes was reversed by treatment with a lysosome inhibitor.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

We tried but failed to show an unquestionable full co-localization of AA / SAA reactivity and the lysosome specific marker LAMP-2.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

These genes encode enzymes that generate the mannose-6-phosphate signal, which directs a diverse group of hydrolases to the lysosome.    From Wordnik.com.  [Medlogs - Recent stories] Reference

The open end of the depression then closes and the newly formed sac moves to the inside of the cell where it fuses with the lysosome.    From Wordnik.com. Reference

We have also shown that GALNS is taken up into human Morquio chondrocytes in vitro and reaches the lysosome to clear keratan sulfate.    From Wordnik.com.  [SeekingAlpha.com: Home Page] Reference

NAGPA, which is also linked to the lysosome, was associated for the first time in this study with a disorder in humans -- stuttering.    From Wordnik.com.  [canada.com Top Stories] Reference

Together, these enzymes make up the signaling mechanism that cells use to steer a variety of enzymes to the lysosome to do their work.    From Wordnik.com.  [EurekAlert! - Breaking News] Reference

Taken together, these results show that neither the proteasome nor lysosome plays a role in the ENC1-mediated down-regulation of Nrf2.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The efficiency of lysosome-mediated degradation by monocytes was further evaluated with DQ ™ ovalbumin particles with BODYPY FL dye.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"recycling" enzymes, human alpha-galactosidase or alpha-GAL, as it breaks down substances in the lysosome, the cell's recycling center.    From Wordnik.com.  [Newswise: Latest News] Reference