Although, at this time, it was known that the thyroid gland is atrophied in myxoedema and in cretinism, it was not until 1892 that Murray discovered that administration of the gland removes the symptoms, and it was only later that the doctrine of internal secretions, first enunciated by Claude Bernard in 1856 in connection with the production of sugar by the liver, came to take its place in physiological teaching.    From Wordnik.com.  [John Macleod - Nobel Lecture] Reference

If too little thyroxin is produced myxoedema BMR may shrink to 30-40 percent of normal.    From Wordnik.com.  [Link Farm and Open Thread #10] Reference

Various morbid conditions are explained by this, among which are cretinism and myxoedema.    From Wordnik.com.  [Nobel Prize in Physiology or Medicine 1909 - Presentation Speech] Reference

In the early days an operator would occasionally remove too, much gland and then the symptoms, of myxoedema would occur.    From Wordnik.com.  [The Foundations of Personality] Reference

Adverse reports of peripheral neuropathy on the toxicity tests carried out on it; to consider and myxoedema appeared in the literature in late whether any further tests should be made and 1958 and 1959, associated with thalidomide.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference