Interest flowing for a South African to a non-resident connected party should attract a withholding tax, namely a non-resident tax on interest (NRTI), the commission said. From Wordnik.com. [ANC Daily News Briefing] Reference
When an NRTI becomes part of a strand of DNA, the addition of further nucleotides is prevented, a full-length copy of the viral DNA is not produced, and viral replication is interrupted. From Wordnik.com. [Analog Science Fiction and Fact]
Table 2 shows the updated list of 34 NRTI SDRMs at 15 RT positions. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Inc. (OTCBB: NRTI), a leader in targeted product development for the Clinical. From Wordnik.com. [The Earth Times Online Newspaper] Reference
Apricitabine (ATC) is an anti-HIV nucleoside reverse transcriptase inhibitor (NRTI). From Wordnik.com. [Health News from Medical News Today] Reference
The phase III trail was initiated in January 2008, in patients with NRTI resistance. From Wordnik.com. [New Statesman] Reference
The updated SDRM list has 93 mutations including 34 NRTI-resistance mutations at 15 RT positions, 19. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Six nonpolymorphic NRTI-resistance mutations including E44A, D67E, T69N, K70E, L74I, and K219N were not present on the 2007 SDRM list. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
No statistically significant differences were seen in percent change in limb fat between the NRTI arms by intent-to-treat or as-treated analyses. From Wordnik.com. [Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7] Reference
NRTI-associated mutations that are clustered around the active site confer decreased, e.g. M184V and Y115F, or increased, e.g. K65R, susceptibility to INDOPY-1. From Wordnik.com. [Journal of Biological Chemistry current issue] Reference
Patients who entered the study were 16 years or older with documented resistance to at least one drug in each of the three oral classes of ARVs (NNRT, NRTI, PI). From Wordnik.com. [Medlogs - Recent stories] Reference
HIV strains with pan-NRTI resistance were sensitive to CMX157, and no antagonistic interactions were observed between CMX157 and any currently approved antiretroviral. From Wordnik.com. [Latest News from SYS-CON MEDIA] Reference
Two of these studies were conducted in clinically advanced, 3-class antiretroviral (NNRT, NRTI, PI) treatment-experienced adults and one was conducted in treatment-naïve adults. From Wordnik.com. [Medlogs - Recent stories] Reference
However, it has been reported in only six NRTI-experienced and nine NRTI-naïve individuals, amd its prevalence was less than 0. 1\% among sequences from treated individuals in any subtype. (ii). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Overall, 5.6 percent of subjects had greater than or equal to 1 fracture (all traumatic), with no significant differences in fracture rates between the NRTI arms (p = 1.0), or between EFV vs. ATV/RTV arms. From Wordnik.com. [Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7] Reference
ATC is Avexa's lead program and has successfully completed the 96 week dosing of its Phase IIb clinical trial and commenced its Phase III trials worldwide in January 2008 in HIV patients with NRTI resistance. From Wordnik.com. [Health News from Medical News Today] Reference
Although they occur at polymorphic positions, we included in the list the NRTI mutations T69D, the T69 insertions, and V75T / M / A / S, because of their substantial contribution to resistance to commonly-used NRTIs. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The study participants will be experienced HIV-1 infected individuals who are failing current therapy and have documented resistance to at least one agent in each of the 'classic' three ARV classes (NRTI, NNRTI, PI). From Wordnik.com. [News] Reference
The 2009 list contains 77 of the 80 mutations on the 2007 list and 16 additional mutations including four new NRTI-associated resistance mutations (D67E, K70E, L74I, and K219N), three new NNRTI-associated resistance mutations. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Of 21 treated seroconverters with antiretroviral-resistant HIV strains, 16 had single-class resistance (NRTI = 10, NNRTI = 6), 4 had dual-class resistance (NRTI and NNRTI), and 1 had triple-class resistance (NRTI, NNRTI, and PI). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Both studies in treatment-experienced patients were conducted in clinically advanced, 3-class antiretroviral-experienced (NRTI, NNRTI, PI, or enfuvirtide) adults with evidence of HIV-1 replication despite ongoing antiretroviral therapy. From Wordnik.com. [Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7] Reference
Several known NRTI-resistance mutations were excluded from consideration as an SDRM: (i) K65N is a recently described rare NRTI-resistance mutation, which was present on two expert lists and which appears to have a phenotypic effect similar to K65R. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Different strategies of ritonavir-boosted lopinavir monotherapy have been explored; however, data regarding salvage therapy among HIV-infected patients who failed nucleoside reverse transcriptase inhibitor (NRTI) and non-nucleoside reverse transcriptase inhibitor. From Wordnik.com. [BioMed Central - Latest articles] Reference
The updated 2009 SDRM list developed in this analysis has 93 mutations including 34 NRTI-associated resistance mutations at 15 RT positions, 19 NNRTI-associated resistance mutations at 10 RT positions, and 40 PI-associated resistance mutations at 18 protease positions. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Overall, 75 mutations were on five lists including 17 NRTI, 18 NNRTI, and 40 PI-associated mutations; 43 mutations were on four lists including 11 NRTI, 8 NNRTI, and 24 PI-associated mutations; and 42 mutations appeared on three lists including 17 NRTI, 11 NNRTI, and 14 PI-associated mutations. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Although protease inhibitors specifically designed to inhibit HIV-encoded protease do not affect XMRV infection and replication, nor do non-nucleoside reverse-transcriptase inhibitors (NNRTI), XMRV is susceptible to the nucleoside reverse-transcriptase inhibitors (NRTI) azidothymidine (AZT) but not tenofovir in one study. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Of these 16 new mutations, nine owe their recognition to specific trends in ARV development and usage: the increased use of non-thymidine containing NRTI regimens (K70E and L74I), the increased recognition of mutations associated with etravirine (K101P, V179F and Y181V), tipranavir (V82L and N83D), and darunavir (L76V) resistance. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
(d4T), together with didanosine (ddI), as part of their first nucleoside reverse transcriptase inhibitor (NRTI) - based regimen (Group 1). From Wordnik.com. [BioMed Central - Latest articles] Reference
In order to achieve the maximum flexibility in tailoring therapy to each patient over the duration of his or her infection, it is imperative that drug formularies allow for all FDA-approved NRTI, NNRTI, and PI as treatment options. ". From Wordnik.com. [ANC Today] Reference
Combined Marketed Product Portfolio Combined Clinical Development Pipeline Product Class Product Class Phase Agenerase Protease inhibitor GSK 1349572 Integrase II inhibitor Combivir NRTI UK-453061 NNRTI II Epivir / 3TC NRTI GSK 2248761 NNRTI II. From Wordnik.com. Reference
NRTI), a leader in targeted product development for the Clinical Nutrition and Sports. From Wordnik.com. [News] Reference
Epzicom / Kivexa NRTI PF-232798 CCR5 antagonist II Lexiva / Telzir Protease inhibitor PF-3716539 PK enhancer I Rescriptor NNRTI (US only) GSK706769 CCR5 antagonist I Retrovir / AZT NRTI Selzentry / Celsentri CCR5 antagonist Trizivir NRTI Viracept Protease inhibitor. From Wordnik.com. Reference
(Ritonavir, Saquinavir, or Indinavir), nucleoside reverse transcriptase inhibitors (NRTI, AZT. From Wordnik.com. [Watching the Watchers] Reference
There were 39 nonpolymorphic NRTI-associated drug resistance mutations present on three or more expert lists (http: / / hivdb. stanford.edu / cgi-bin / AgMutP rev. cgi. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
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