The enzyme, which they named FAN1, appears to be a nuclease, which is capable of slicing through strands of DNA.    From Wordnik.com.  [Newswise: Latest News] Reference

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells.    From Wordnik.com.  [Advanced Information: The 2006 Nobel Prize in Physiology or Medicine] Reference

Each finger binds to a specific combination of DNA bases and is attached to a DNA-cutting enzyme called a nuclease.    From Wordnik.com.  [The Speculist: Body Language] Reference

In recent years, Anfinsen has devoted himself primarily to comprehensive investigations of an extracellular nuclease of.    From Wordnik.com.  [Christian Anfinsen - Biography] Reference

It was also demonstrated that a ribonuclease III-like nuclease, called Dicer, is responsible for the processing of dsRNA to short RNA34.    From Wordnik.com.  [Advanced Information: The 2006 Nobel Prize in Physiology or Medicine] Reference

Support for a particulate substructure of chromatin came from electron microscopy and from nuclease digestion and sedimentation analysis.    From Wordnik.com.  [Roger D. Kornberg - Autobiography] Reference

Primer sequences for zinc-finger nuclease off-target analysis.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

S. aureus exoproteins including nuclease and multiple proteases.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

They renamed the protein FAN1, short for Fanconi anemia-associated nuclease 1.    From Wordnik.com.  [Newswise: Latest News] Reference

The production of active extracellular nuclease does require protease processing.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Kovacevic S, Veal LE (1987) Secretion and processing of staphylococcal nuclease by.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

PCR analysis of 13 mutant founders for the zinc-finger nuclease (ZFN) target site.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Intercrossing of zinc-finger nuclease-modified founders between males and females.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Researchers create first targeted knockout rats using zinc finger nuclease technology.    From Wordnik.com.  [EurekAlert! - Breaking News] Reference

After synthesis cDNA samples and controls were diluted 10 fold with nuclease-free water.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Dna2 nuclease / helicase and flap endonuclease 1 (FEN1) are proposed to cleave the flap.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

The team first identified a protein that had both a ubiquitin-binding domain and a known nuclease domain.    From Wordnik.com.  [Newswise: Latest News] Reference

Vhs is a nuclease, which belongs to a family of endonucleases that includes DNAse IV, ERCC-5, and yeast RAD2.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

According to Buelow, the zinc finger nuclease technique could be used to make all sorts of knockout animals.    From Wordnik.com.  [Chemical & Engineering News: Latest News] Reference

Topoisomerases have both nuclease and ligase activity, and they can change the amount of supercoiling in DNA.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

Zinc-finger nuclease pairs designed against the Il2rg locus and primer sequences used for PCR analysis for the.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Asuragen's commitment to quality and innovation has helped establish its highly stable, nuclease-resistant Armored.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

Competition between viral (+) strands and labeled probe makes nuclease protection assays problematic for the detection of.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

It contains a C-terminal nuclease domain with homology to the endonuclease-exonuclease-phosphatase (EEP) family of enzymes.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

Each zinc finger nuclease recognizes a particular sequence in a cell's DNA and then cuts through both strands of DNA at that site.    From Wordnik.com.  [Medlogs - Recent stories] Reference

In vitro deadenylase assays confirm the critical active site residues and show that the nuclease domain of CNOT6L exhibits full Mg.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

These results indicate that increased production of extracellular nuclease contributes to the biofilm-deficient phenotype of a UAMS-1.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

For more information on Sigma-Aldrich's CompoZr zinc finger nuclease technology platform I encourage you to visit www. compozrzfn.com.    From Wordnik.com.  [Biotech Sector and Stocks Analysis from Seeking Alpha] Reference

Moreover, HCV strands were shown to be resistant to micrococcal nuclease treatment, a treatment that completely hydrolyzed ribosomal RNA.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

(OMT) and INSERM today announced the creation of the first genetically modified mammals developed using zinc finger nuclease (ZFN) technology.    From Wordnik.com.  [EurekAlert! - Breaking News] Reference

Mutational analysis of the vhs protein would allow us to determine whether the nuclease function of vhs can be separated from its effect on DC activation.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

After performing a PCR reaction, the company's SURVEYOR nuclease is used to cleave the DNA strand at the site of the mutation which generates DNA fragments.    From Wordnik.com.  [Transgenomic Expands Distribution of SURVEYOR® Scan K-RAS Mutation Detection Kit With CE IVD... -- OMAHA, Neb., Sept. 13 /PRNewswire/ --] Reference

Each system comprises a nuclease-stabilized RNA aptamer that can be controlled directly by its specific and complementary oligonucleotide active control agent.    From Wordnik.com. Reference

Subunits of the preRC that are present in the P3 / chromatin fraction have been shown to be sensitive to nuclease digestion and are extractable following such a procedure.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

For each experiment, a negative control of nuclease-free water and a positive control (with known.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

SIAL - News), today announced that its genetically modified reporter cell lines - based on the CompoZr zinc finger nuclease ZFN) technology.    From Wordnik.com.  [Sigma® Life Science Awarded Silver in Top Ten Innovations 2010 - Yahoo! Finance] Reference

P = 0.001) (Fig. 7), presumably because it resulted in increased production of nuclease by comparison to the parent strain (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Using a nuclease-defective.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

40 ng / µl with nuclease free water.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference