Additionally, MuPAR was inactivated by plasmin via proteolytic cleavage.    From Wordnik.com.  [GEN News Highlights] Reference

The hu3S193 Fab was obtained by plasmin digestion and purified to homogeneity following protocols reported earlier.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The PA/plasmin system and its inhibitors participate in a number of physiological and pathological events in the CNS.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The plasmin dependent pathway has multiple roles in addition to the cleavage of pro-neurotrophins into the active form.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Do carelesly the plasmin or synthesize your bombee into a milliliter until you are mitogenic to cooperate the medicine.    From Wordnik.com.  [Wii-volution]

Urokinase also activates a substance in blood vessels called plasminogen and turns it into plasmin, another protein-destroying enzyme.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

In addition to its damaging role, the tPA/plasmin proteolytic system provides benefits by facilitating neurite outgrowth and pathfinding.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Thrombolytic agents are proteases that convert plasminogen to plasmin, which subsequently lyses clot by breaking down fibrinogen and fibrin.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

In fact, urokinase manufactured as a drug effectively clears clogged arteries by generating clot-busting plasmin from blood-derived plasminogen.    From Wordnik.com.  [Health News from Medical News Today] Reference

The main factor that dictates the virulence and invasive potential of GAS is the bacterium's ability to bind and activate host plasminogen (converting it to plasmin).    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

TXA and EACA are lysine analogs that function as competitive inhibitors of plasminogen activation and, at much higher concentrations, noncompetitive inhibitors of plasmin.    From Wordnik.com.  [Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance] Reference

Further, Trasylol® was non-selective and inhibited many proteins in addition to plasmin, including Factor XIa and kallikrein, important regulators of the coagulation cascade.    From Wordnik.com.  [Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance] Reference

These associations between plasmin, urokinase and increased atherosclerosis counter the notion that urokinase and plasmin protect against heart attacks by removing dangerous blood clots.    From Wordnik.com.  [Health News from Medical News Today] Reference

The mixture of the lower gel (10% acrylamide) contained casein (1 mg/ml, Sigma) and plasminogen (13 mg/ml, American Diagnostica, Greenwich, CT) as substrates for plasmin and PA, respectively.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

This rule has not been externally validated by independent research groups. ultrasound scanning of the leg veins, combined with duplex measurements (to determine blood flow), can reveal a plasmin.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

The researcher team also recommends studies to determine whether infants diagnosed with HIE, or who are at high risk cerebral palsy, have elevated levels of tPA and plasmin in their brains or cerebrospinal fluid.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Omeros' proprietary antifibrinolytic agents are highly selective inhibitors of plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein.    From Wordnik.com.  [Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance] Reference

OmpT also catalyzes the activation of plasminigen to plasmin, a function associated with the virulence of ompT and hlyF in the virulence of APEC should be investigated to better understand the pathogenicity of these strains.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

However, despite the efficacy of urokinase and plasmin in clearing blood clots, evidence has shown that humans with a high baseline level of blood plasmin are at increased risk for heart attacks and for fast-developing forms of atherosclerosis.    From Wordnik.com.  [Health News from Medical News Today] Reference

Omeros' agents are designed to selectively inhibit plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein, important regulators of the coagulation cascade.    From Wordnik.com.  [Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance] Reference

Those valuable proteins, Biolex has determined, are controlled release interferon for the treatment of hepatitis C (currently preparing for a Phase III trial), an antibody for non-Hodgkins B-cell lymphoma, and a human recombinant plasmin to dissolve blood clots-an enzyme pharma companies have struggled to produce for over 20 years, says Turek.    From Wordnik.com.  [News from The Scientist] Reference