The transfusion of aged, more rigid, red blood cells has been associated with decreased gastric intramucosal pH and may act to accentuate the rheologic abnormalities seen in sepsis. 31 Moreover, a study51 randomizing critically ill patients to transfusion thresholds of 7.0 and 10 g / dL failed to demonstrate any differences in clinically significant outcomes. From Wordnik.com. [Recently Uploaded Slideshows] Reference
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