Now being added to the list: Bubble-boy disease, formally known as SCID for severe combined immune deficiency. From Wordnik.com. [Canadian Online Health News] Reference
Left undiagnosed, a newborn with SCID, which is a group disorder, usually will die within the first year of life. From Wordnik.com. [The Fond du Lac Reporter Latest Headlines] Reference
I swear, I have the immune system of a SCID mouse. From Wordnik.com. [Chicken Noodle Ramen for the Sick] Reference
Yup, that's SCID as in severe combined immunodeficinecy. From Wordnik.com. [Chicken Noodle Ramen for the Sick] Reference
Those who survived were cured of SCID-X1, but the episode prompted the U.S. From Wordnik.com. [Study Shows Hope for Gene Therapy] Reference
One should still be cautious here: SCID is a rare condition amenable to correction with a single gene. From Wordnik.com. [How Sick Is Modern Medicine?] Reference
Successful use of extracorporeal membrane oxygenation (ECMO) as a bridge to reconstitution following BMT for SCID. From Wordnik.com. [Fetal Stem Cell Transplantation, In Utero Stemm Cell Publications] Reference
In a recent report, the delivery of normal genes to two infants with SCID corrected their abnormal immune function. From Wordnik.com. [How Sick Is Modern Medicine?] Reference
Treatment of X-linked Severe Combined Immunodeficiency (X-SCID) by the in utero transplantation of paternal bone marrow. From Wordnik.com. [Fetal Stem Cell Transplantation, In Utero Stemm Cell Publications] Reference
X-linked SCID severe combined immune deficiency is also called bubble-boy syndrome because it almost never occurs in females. From Wordnik.com. [Jonathan Wells: Another ID Creationist Who Doesn't Understand Information Theory - The Panda's Thumb] Reference
These children have what's called severe combined immune deficiency (SCID) disorder, more commonly known as bubble boy disease. From Wordnik.com. [Excerpt: More Than Human by Ramez Naam] Reference
Currently, SCID-X1 is treatable only by bone-marrow transplantation, preferably from a sibling who is an exact bone-marrow match. From Wordnik.com. [Study Shows Hope for Gene Therapy] Reference
Meantime, St. Jude Children's Research Hospital, Memphis, Tenn., is planning a separate gene-therapy trial for infants with SCID-X1. From Wordnik.com. [Study Shows Hope for Gene Therapy] Reference
I use diabetes as a well-known example, for which there appears to be genetic predisposition rather than genetic cause, as in SCID or CF. From Wordnik.com. [Candidates Lay Out Ideas On Health Care In Vegas] Reference
Histology of chimeric SCID/uPA liver at 12 weeks old. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Impact of vTK/GCV on non transplanted SCID/uPA mouse liver. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In vivo engraftment of the expanded HSPCs in NOD/SCID mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Induction of apoptosis by vTK/GCV in chimeric SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Impact of vTK/GCV on the gross appearance of chimeric SCID/uPA liver. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Histopathological changes induced by vTK/GCV in chimeric SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
SCID/uPA mice and vTK+ SCID/uPA mice that did not receive GCV (not shown). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Impact of vTK/GCV on serum aminotranserases levels in chimeric SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
VSVG-pseudotyped lentivirus to deliver human factor IX to non-chimeric SCID mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Thus, we reproduced the HSV tk (vTK)/GCV system of hepatic failure in SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
OPN-A (middle) and OPN-A-RAA (right) cells were injected into the tail veins of SCID mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
MiaPaCa-2 (left) and HT1080 (right) cells were injected into the flank of SCID mice (n = 5). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
For in vivo experiments, expression of vTK was targeted to the livers of FVB/N and SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Impact of vTK/GCV on hAAT production and human hepatocyte engraftement in chimeric SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
(NOD/SCID) mouse-repopulating cells (SRCs), and long-term primate hematopoietic repopulating cells. From Wordnik.com. [Naturejobs - All Jobs] Reference
C-D. vTK+ SCID/uPA livers with no GCV showing normal cellular (C) and mitochondrial (D) ultrastructure. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Limited survival beyond 3 months post-transplant has been described for chimeric SCID/uPA mice with RI >. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The specific characteristics of SCID make this disease uniquely amenable to a prenatal stem cell approach. From Wordnik.com. [PhysOrg.com - latest science and technology news stories] Reference
Zygosity of SCID mutation and uPA transgene was determined in offspring by established PCR based strategies. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
For SCID/uPA mice, normal hepatic capacity is restored by the development of RN, be they from uPA-deficient MH or HH. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Stars indicate p Both MiaPaCa-2 and HT1080 cells were injected subcutaneously into SCID mice and tumor growth was monitored. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
We have developed the SCID/uPA mouse model of human liver, based on transgenic mice in which uPA expression is targeted to hepatocytes. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Hepatic sensitivity to GCV was first established in FVB/N mice since these mice do not undergo liver failure inherent to SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Overexpression of either OPN-A or B in two different cell types promoted local tumor growth and lung metastasis in SCID mouse xenografts. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The average pre-dose ALT/AST values for all vTK − and vTK+ chimeric mice were within the range of the non-transplanted vTK-SCID/uPA mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
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