Hepatic transaminase elevations are also common; alone, however, they are unrelated to hepatic toxicity and have no clinical significance. From Wordnik.com. [The Neuropsychiatric Guide to Modern Everyday Psychiatry] Reference
ALT (alanine transaminase)/SGPT (serum glutamic pyruvic transaminase) - measures the amount of this enzyme, which the liver produces and stores. From Wordnik.com. [Laboratory tests for liver transplant patients] Reference
AST (aspartate transaminase)/SGOT (serum glutamic-oxaloacetic transaminase) - measures the amount of this enzyme, which the liver (along with other organs) produces and stores. From Wordnik.com. [Laboratory tests for liver transplant patients] Reference
Because transient elevations of serum transaminase levels have been observed during the course of succimer therapy, serum transaminases should be monitored prior to the initiation of therapy and at least weekly during therapy, particularly in patients with a history of liver disease. From Wordnik.com. [Succimer] Reference
Laboratory evaluations including urinalysis, alanine transaminase. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Activity creatine phosphokinase glutamic oxaloacetic transaminase serum calves. From Wordnik.com. [xml's Blinklist.com] Reference
If levels of ALT (alanine transaminase) are high the patient may have hepatitis. From Wordnik.com. [Health News from Medical News Today] Reference
Aspartate Aminotransferase (AST) - previously known as serum glutamic-oxaloacetic transaminase (SGOT). From Wordnik.com. [Recently Uploaded Slideshows] Reference
GABA is transported in the mitochondria to be converted into succinic semialdehyde (SSA) by a GABA transaminase. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
We identified the GABA transaminase (GABA-T), the first step of GABA catabolism, as the most responsive to NaCl. From Wordnik.com. [BioMed Central - Latest articles] Reference
Some interpreters cited the elevation of liver transaminase enzyme in 12% of patients the reason for the sell-off. From Wordnik.com. [BNET Articles] Reference
Alternatively, given that an α-ketoglutarate-dependent GABA transaminase exists, SSA could be converted to GABA, too. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Leading the way is Sabril (R) (vigabatrin), a GABA-transaminase inhibitor that is effective in reducing epileptic seizures. From Wordnik.com. [The Earth Times Online Newspaper] Reference
A dose-dependent, mild increase in hepatic transaminase levels was observed, a finding that will be monitored in future trials. From Wordnik.com. [News] Reference
Patients with hepatitis B or C or marked elevations in transaminases are at risk of further transaminase elevations or hepatic decompensation. From Wordnik.com. Reference
Through directed evolution, Codexis developed a transaminase enzyme that acts as an efficient biocatalyst for transforming ketone into sitagliptin. From Wordnik.com. [Business Wire Travel News] Reference
Sabrilsabril (vigabatrin) is an direct irreversible gaba-transaminase for the change of infantile spasms and retinoid complex administrative seizures. From Wordnik.com. [Wii-volution] Reference
There was a significant association of IL-8 levels with thrombocytopenia and both IFN-γ and IL-8 were positively associated with alanine transaminase levels. From Wordnik.com. [Elites TV] Reference
Patients with isolated elevations of transaminase 1.5 X ULN also had a higher rate of febrile neutropenia grade 4 but did not have an increased incidence of toxic death. From Wordnik.com. [Sanofi-aventis Oncology Data to be Presented at San Antonio Breast Cancer Symposium - Yahoo! Finance] Reference
The treatment naïve group with high viral load receiving the triple therapy also saw a 14 percent advantage over the SOC group in normalization of alanine transaminase (ALT). From Wordnik.com. [Health News from Medical News Today] Reference
The treatment naive group with high viral load receiving the triple therapy also saw a 14 percent advantage over the SOC group in normalization of alanine transaminase (ALT), a marker of liver damage. From Wordnik.com. [GEN News Highlights] Reference
Compared to patients from adult clinical trials, adolescents were also likely to experience increased sedation and greater increases in prolactin levels and hepatic transaminase (liver enzymes) levels. From Wordnik.com. Reference
Furthermore, increased availability of BCAAs in knockout mice harboring a deletion of mitochondrial BCAA transaminase (BCATm) preserved muscle insulin sensitivity in response to long-term high-fat feeding. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Efficacy was assessed by normalization of serum alanine transaminase (ALT) levels and the non-detectability of serum hepatitis B virus DNA or HBeAg at the end of treatment and 24 weeks after stopping treatment. From Wordnik.com. [BioMed Central - Latest articles] Reference
There were no prognostic hindlimbs in the convulsions of allopurinol tab 300mg g between the 2 transaminase groups, with the neonatal sarcoma of traces extent which was reported fewer frequently for pentostatin (8%) than for ifn (1%). From Wordnik.com. [Wii-volution] Reference
Compared to patients from adult clinical trials, adolescents were likely to gain more weight, experience increased sedation, and have greater increases in total cholesterol, triglycerides, LDL cholesterol, prolactin and hepatic transaminase levels. From Wordnik.com. Reference
While the previous generation of p38 MAPK inhibitors suffered from side effects such as liver transaminase elevations, the newer inhibitors are more selective at targeting p38 and include non-ATP competitive inhibitors directed against the conformation epitope. From Wordnik.com. [Digital50.com Digital 50 Daily Industry News RSS Feed] Reference
Liver enzymes should be monitored before and during treatment in patients with underlying hepatic disease, including hepatitis B or C infection; in patients with marked transaminase elevation; and when Atripla is administered with ritonavir or other medications associated with liver toxicity. From Wordnik.com. [Quad HIV-kuur Gilead in één tablet handhaaft hoge mate virussuppressie] Reference
The authors used reference levels to measure "blood lactate and pyruvate, plasma alanine, urinary organic acids, CK (creatine kinase) AST (aspartate transaminase) and ALT (alanine aminotransferase," they wrote. From Wordnik.com. [David Kirby: NEW STUDY - "Mitochondrial Autism" is Real; Vaccine Triggers Cannot Be Ruled Out] Reference
Enzymes catalysing reactions are numbered, (1) glutamate decarboxylase (GAD), (2) γ-aminobutyric transaminase (GABA-T), (3) succinic semialdehyde dehydrogenase (SSADH) and (4) succinic semialdehyde reductase (SSR). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
4 and 13 of the experiment, transaminase and alkaline phosphatase levels increased in the plasma. From Wordnik.com. [5 Uses] Reference
In study 206 the incidence of alanine transaminase (ALT) levels greater than five times the upper limit of normal (>. From Wordnik.com. [Health News from Medical News Today] Reference
No with stereotypic establecer transaminase throes (ast, alt) at yohimbine lleguen seizers to youngerbroader than 3 windows the internal apariencia of respectable (uln) during colitis with niaspan. 7% with a from 1 % to 20%) of non-scalp regions. From Wordnik.com. [Wii-volution] Reference
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