The intact gland contains an inactive precursor trypsinogen, which is converted into the protein-dissolving enzyme trypsin only by contact with duodenal juice.    From Wordnik.com.  [OUPblog] Reference

Cheng, in 1998, described the evolution of diverse antifreeze proteins in Antarctic fish, one of which was co-opted from a digestive enzyme called trypsinogen.    From Wordnik.com.  [A Word About Intelligent Design Creationism - The Panda's Thumb] Reference

The trypsinogen system was investigated (with Bode) in great detail by low temperature crystallography, gamma-ray spectroscopy, chemical modification, and molecular dynamics calculations.    From Wordnik.com.  [Robert Huber - Autobiography] Reference

I found this interesting , not only because of the evolutionary implications, but also because protease zymogens like trypsinogen act as autocatalytic systems in organisms like me and you, Sal: trypsinogen enters the small intestine, and gets a peptide bond cloven and breaks down into trypsin.    From Wordnik.com.  [Vacuity of ID: Comments on Irreducible Complexity - The Panda's Thumb] Reference

A remarkable twist to this conventional gene-duplication/sequence-divergence paradigm is the creation of a unique functional antifreeze glycoprotein (AFGP) sequence from partly non-coding DNA in Antarctic notothenioid fish, involving de novo duplications of a 9-nt sequence spanning an exon-intron junction of an ancestral trypsinogen-type protease gene to form a large, highly repetitive (ThrAlaAla)n coding region, and shedding most of the protease gene structure.    From Wordnik.com.  [Evolutionary Scrap-heap Challenge: Antifreeze Fish Make Sense Out Of Junk DNA - The Panda's Thumb] Reference

The pediatrician later learned that she did have some minor elevation of trypsinogen and lipase with normal renal function tests, but one week later these had normalized and her amylase was now down to 240 U / L.    From Wordnik.com.  [Medlogs - Recent stories] Reference