"For instance, platelets might deliver an enzyme called urokinase to selectively disintegrate blood clots.".    From Wordnik.com.  [THE MEDICAL NEWS] Reference

UW researchers learned that, inside some advanced plaques, macrophages that overproduce a protein-digesting enzyme known as urokinase into aged, atherosclerotic mice.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

In a mouse study, Dickek and his team transplanted bone marrow containing macrophages that overproduce a protein-digesting enzyme known as urokinase into aged, atherosclerotic mice.    From Wordnik.com.  [innovations-report] Reference

The first is a magnetic nanoparticle designed to target a molecule known as urokinase plasminogen activator receptor.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Effect of thrombin, the thrombin receptor activation peptide, and other mitogens on vascular smooth muscle cell urokinase receptor mRNA levels.    From Wordnik.com.  [Behe vs Sea Squirts - The Panda's Thumb] Reference

They have also been studied for their ability to inhibit urokinase, a protein produced by cancer cells that helps them invade healthy cells and spread.    From Wordnik.com.  [Simple Skin Beauty] Reference

Ragno P (2006) The urokinase receptor: a ligand or a receptor?.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Kummel TA, Orlando RA, Farquhar MG (2001) Direct binding of occupied urokinase receptor.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

In addition, human arteries affected by atherosclerosis have an abundance of urokinase.    From Wordnik.com.  [Health News from Medical News Today] Reference

On September 23, 2008, the Company divested its urokinase assets to Microbix Biosystems, Inc.    From Wordnik.com.  [News] Reference

ITA's shuttle payload was experimental hardware designed to grow high-quality urokinase crystals.    From Wordnik.com.  [SPACE.com] Reference

Like urokinase, MMPs have helpful roles, depending on the location and circumstances in the body.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

Suh TT, Nerlov C, Dano K, Degen JL (1994) The murine urokinase-type plasminogen activator receptor gene.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

KINLYTIC (TM) (urokinase), a thrombolytic agent indicated for the treatment of acute massive pulmonary embolism.    From Wordnik.com. Reference

Since that agreement was signed, however, ITA's urokinase experiments have been carried on only three shuttle flights.    From Wordnik.com.  [SPACE.com] Reference

Hypoxia induces expression of the urokinase receptor (uPAR) and activates uPAR-dependent cell signaling in cancer cells.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Despite the loss of the Columbia experiment, Cassanto has not given up on his goal of growing urokinase crystals in space.    From Wordnik.com.  [SPACE.com] Reference

Early in November, Microbix announced that KINLYTIC (urokinase for injection) was approved in Canada for marketing and export.    From Wordnik.com.  [BioSpace.com Featured News and Stories] Reference

Nevertheless, Cassanto continues pressing the space agency for one last chance to grow urokinase crystals on the space shuttle.    From Wordnik.com.  [SPACE.com] Reference

With all outstanding manufacturing issues resolved, Microbix is now the only worldwide source of low-molecular-weight urokinase.    From Wordnik.com.  [BioSpace.com Featured News and Stories] Reference

Scientists have identified 64 proteins believed to be linked with well-known cancer kingpin urokinase plasminogen activator receptor or uPAR.    From Wordnik.com.  [India eNews] Reference

In fact, urokinase manufactured as a drug effectively clears clogged arteries by generating clot-busting plasmin from blood-derived plasminogen.    From Wordnik.com.  [Health News from Medical News Today] Reference

Microbix has submitted an application to Health Canada for approval of its acquired urokinase inventory and targets its release for mid-year 2010.    From Wordnik.com.  [BioSpace.com Featured News and Stories] Reference

The researchers found that injection of PAI-1 greatly reduced the activity of both tPA and another brain enzyme, urokinase-type plasminogen activator.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

O'Donnell DM, Gonias S (2003) Epidermal growth factor receptor-dependent and independent cell signalling pathways originating from the urokinase receptor.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Hall A (2001) Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Furthermore, these cells showed decreased levels of urokinase-type plasminogen activator receptor (uPAR) and increased levels of plasminogen activator inhibitor-1 (PAI-1).    From Wordnik.com.  [Elites TV] Reference

In this study, the therapeutic potential of siRNA-mediated targeting of matrix metalloproteinase-9 (MMP-9), urokinase plasminogen activator receptor (uPAR), and cathepsin B.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

In 2008, Microbix completed the acquisition of all urokinase assets from ImaRx Therapeutics, Inc., making Microbix the only worldwide source of low-molecular-weight urokinase.    From Wordnik.com.  [BioSpace.com Featured News and Stories] Reference

At that same time, the Company indicated it would explore strategic alternatives for its commercial urokinase assets, clinical-stage SonoLysis program as well as its other assets.    From Wordnik.com.  [News] Reference

Naturally produced in the body, urokinase plasminogen activator and plasminogen interact to break up blood clots and recruit clean-up cells to clear away debris related to inflammation.    From Wordnik.com.  [Health News from Medical News Today] Reference

urokinase-type Plasminogen activator (uPa): forward.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

(2002) Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

(2006) LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

urokinase, 187.    From Wordnik.com.  [Simple Skin Beauty] Reference