(Catharanthus roseus) is a source of at least 60 alkaloids, of which the two important alkaloids, vincristine and vinblastine, have revolutionized the treatment of childhood leukemia and hodgkin's disease.    From Wordnik.com.  [Chapter 7] Reference

This herbaceous plant, native to South-eastern Madagascar, is a source of over 75 alkaloids, two of which, vincristine and vinblastine, are used to treat childhood leukemia and Hodgkin's disease, with a significant success rate.    From Wordnik.com.  [Chapter 7] Reference

For the past decade, a modified chemotherapy regimen consisting of cyclophosphamide, vincristine, procarbazine and prednisone (COPP), together with adriamycin, bleomycin and vinblastine (ABV) has been used to treat patients with HD.    From Wordnik.com.  [Completed studies on late effects of childhood cancer] Reference

One class of anti-inflammatory agents is microtubule-disrupting agents such as colchicine and vinblastine.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

ZIO 301 takes aim at the taxanes (paclitaxel, docetaxel) and the Vinca alkaloids (vincristine, vinblastine).    From Wordnik.com.  [SeekingAlpha.com: Home Page] Reference

Nucleoside analogues are associated with nephrotoxicity but have shown to be synergistic with other therapies such as vinblastine.    From Wordnik.com.  [SeekingAlpha.com: Home Page] Reference

The phase I combination trial will evaluate brentuximab vedotin plus Adriamycin (doxorubicin), bleomycin, vinblastine and dacarbazine.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

The phase I clinical trial will be evaluating Brentuximab Vedotin in combination with Adriamycin, bleomycin, vinblastine and dacarbazine (ABVD).    From Wordnik.com.  [New Statesman] Reference

However, the combination chemotherapy regimen referred to as MVP (mitoxantrone, vinblastine, and cisplatin) does not provide any benefit for patients with this disease.    From Wordnik.com. Reference

The phase I combination trial will evaluate brentuximab vedotin plus Adriamycin (doxorubicin), bleomycin, vinblastine and dacarbazine (ABVD), a commonly used front-line chemotherapy regimen for Hodgkin lymphoma.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Rowley relied instead on the unique quinacrine staining patterns that appeared on partly elongated chromosomes generated by brief treatment of patient cells with the microtubule polymerization inhibitor, vinblastine.    From Wordnik.com.  [ScienceBlogs Channel : Life Science] Reference

Another tubulin inhibitor, vinblastine, used in the treatment of hematological malignancies, has significant toxic side-effects such as leucocytopenias, gastrointestinal toxicity, peripheral neuropathy and immunosuppression.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Chambers TC (2005) Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The U.S. National Cancer Institute (NCI) recently tested reovirus in combination with a wide range of common chemotherapeutic agents against NSCLC, and found that the combination of reovirus with cisplatin, gemcitabine, mitomycin or vinblastine was synergistic against NSCLC cell lines that were sensitive to the compounds.    From Wordnik.com.  [Health News from Medical News Today] Reference

This trial compared the following regimens: doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) for 6 to 8 months, mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) for 6 to 8 months, and MOPP alternating with ABVD for 12 months. 1 The trial was limited to patients with advanced disease (clinical stages III and IV).    From Wordnik.com.  [New England Journal of Medicine] Reference

The company plans to initiate a phase I trial to evaluate the safety of brentuximab vedotin in combination with ABVD (Adriamycin, bleomycin, vinblastine and dacarbazine), the standard front-line chemotherapy regimen for Hodgkin lymphoma, as well as a phase III trial for patients at high risk of residual Hodgkin lymphoma following autologous stem cell transplant, both in the first half of 2010.    From Wordnik.com.  [The Earth Times Online Newspaper] Reference

7Q-htt and 111Q-htt mice untreated or treated with vinblastine were co-stained for LC3 and Mitotracker (.    From Wordnik.com.  [Naturejobs - All Jobs] Reference