Morphological traits such as brachycephaly are characteristic of certain breeds and had a functional purpose at the time that those breeds were created.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

From Central Asia eastward to the Pacific Islands and subcontinents on the one hand, and to America on the other, brachycephaly and orthognathism gradually diminish, and are replaced by dolichocephaly and prognathism, less, however, on the.    From Wordnik.com.  [Essays] Reference

The gene responsible for brachycephaly is unknown.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Fine mapping using haplotype analysis for brachycephaly.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Table S1 for the positive control loci as well as brachycephaly.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Based on crosses performed between breeds, brachycephaly is a semi-dominant trait.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Of the two genes associated with brachycephaly, the most promising candidate gene was THBS2.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Based on the results obtained from the SNP arrays, haplotype analysis was performed for brachycephaly.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

An association between a variant of the canine TCOF1 gene and brachycephaly has been suggested in the past.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Thus the vast majority of heads are mesaticephalic with more tendency toward brachycephaly than to dolichocephaly.    From Wordnik.com.  [The Negrito and Allied Types in the Philippines and The Ilongot or Ibilao of Luzon] Reference

The second candidate gene for brachycephaly, SMOC2, was located just outside of the critical interval for brachycephalic head type.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

There is little variation within these breeds for brachycephaly, indicating that individuals are largely fixed for the causative allele.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

In order to further confirm the chromosome assignment for brachycephaly, a second independent data set was used for genome wide association.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Using the measure of relative heterozygosity by chromosome helped to define the location of a selective sweep around the brachycephaly locus.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

A. - log 10 of the permutated (100,000) p values (y axis) for genome wide association for brachycephaly across dog breeds are plotted by chromosome (x axis).    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Normalized relative heterozygosity (x axis) is plotted against position on CFA 1 in Mb (y axis) using a five SNP sliding window for brachycephaly in the original dataset.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Archeological evidence suggests that brachycephaly existed before the formation of modern breeds so it is likely that the major locus that confers this phenotype is common among affected breeds.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

On the other hand, the Borreby skulls are all somewhat broader, in proportion to their length, than the Neanderthal skull, while some attain that proportion of breadth to length (80: 100) which constitutes brachycephaly.    From Wordnik.com.  [Lectures and Essays] Reference

10 SNP sliding window for brachycephaly in the second independent dataset. doi: 10.1371/journal. pone.0009632.g004.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Bicoronal craniosynostosis causes brachycephaly.    From Wordnik.com.  [The Beauty of Love] Reference

For brachycephaly, three breeds were considered as cases (Pugs, Boxer and Pekingese) and 13 breeds (Afghan Hound.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

(2009) TCOF1 T/Ser variant and brachycephaly in dogs.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

P value for brachycephaly was 2. 44×10 − 36.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

100 more significant than the next highest), successfully identified genomic regions of association for brachycephaly.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference