These are exemplified below with isopropyl chloride which, in the presence of the nucleophile Nu -, reacts to give a nucleophilic substitution product and/or an elimination product.    From Wordnik.com.  [Press Release: The 1994 Nobel Prize in Chemistry] Reference

Drosophila enzyme are observed with a nucleophile-Ala variant with the − 1 subsite sugar.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

You're an electrophile and I'm a nucleophile, we're attracted and we can make each other happy.    From Wordnik.com.  [Chemistry Blog] Reference

Here we report an example of thymidylate biosynthesis that occurs without an enzymatic nucleophile.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

Currently studied sortases accept only one nucleophile to complete their transpeptidation reaction (5-8).    From Wordnik.com.  [Proceedings of the National Academy of Sciences current issue] Reference

The transient product of this reaction is an acyl enzyme that, depending on the sortase involved, is relieved by a specific nucleophile (4).    From Wordnik.com.  [Proceedings of the National Academy of Sciences current issue] Reference

Mg2+ ion A is bound between the γ-phosphate and the Thr/Ser residues that become phosphorylated and shepherds the nucleophile toward the former.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

(the nucleophile) carries an electron pair to the substrate, using this pair to form the new bond while the leaving group departs with an electron pair.    From Wordnik.com.  [Press Release: The 1994 Nobel Prize in Chemistry] Reference

Our findings indicate that the putative active site nucleophile is not required for FDTS catalysis, and no alternative nucleophilic residues capable of serving this function can be identified.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

The pseuoduridine synthases (Y synthases) are responsible for this reaction, and they fall into five families that share very limited sequence similarity but have the same overall fold and active site architecture, including an essential Asp that likely serves as both a nucleophile and a general base during the reaction.    From Wordnik.com.  [eisinc.com] Reference

α − mannosidase II show the − 1 sugar in a 4C1 chair conformation but these have been obtained on a nucleophile-alanine variant so their conformational relevance to catalysis is unclear doi: 10.1371/journal. pone.0009006.g005.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Close examination of a segment in the Ns revealed the addition of no-show, no-win, nucleophile, nuke, number cruncher, nut house, and nuts and bolts, while on the technical side nucleosome, nucleosynthesis, nullipara, and nurturance were added, among others.    From Wordnik.com.  [VERBATIM: The Language Quarterly Vol IX No 3] Reference