A transisthmian railroad was constructed by an American company.    From Wordnik.com.  [11. Panama and the Panama Canal Zone] Reference

Atlantic and the Pacific oceans, has been accompanied by results of a most interesting and impressive nature, and has created new conditions, not in the routes of commerce only, but in political geography, which powerfully affect our relations toward and necessarily increase our interests in any transisthmian route which may be opened and employed for the ends of peace and traffic, or, in other contingencies, for uses inimical to both.    From Wordnik.com.  [State of the Union Address (1790-2001)] Reference

Vast commercial and political consequences will follow the opening of the transisthmian waterway.    From Wordnik.com.  [The American Type of Isthmian Canal Speech by Hon. John Fairfield Dryden in the Senate of the United States, June 14, 1906] Reference

Modern Panamanian history has been shaped by its transisthmian canal, which had been a dream since the beginning of Spanish colonization.    From Wordnik.com. Reference

Under the auspices of the government, M. Lesseps commenced a transisthmian canal, which would open communication between the M.diterranean Sea and the.    From Wordnik.com.  [A Short History of France] Reference

If it is an advantage to gain an hour or two in transit ten years hence by having no transisthmian shipping facilities for the ten years in the meantime, then it might as well be argued that it would be better to project a sea-level canal 300 feet wide at every point, so that the commerce of the year 2000 may be properly provided for.    From Wordnik.com.  [The American Type of Isthmian Canal Speech by Hon. John Fairfield Dryden in the Senate of the United States, June 14, 1906] Reference

A lock canal can be built which will meet all requirements; it can be built deep enough and wide enough to accommodate the largest vessels afloat; it can be so built that transit across the Isthmus can be effected in a reasonably short period of time -- in a word, it is a practical project, which will solve every pending question involved in the construction of a transisthmian canal in a practical way, at a reasonable cost, and within a reasonable period of time.    From Wordnik.com.  [The American Type of Isthmian Canal Speech by Hon. John Fairfield Dryden in the Senate of the United States, June 14, 1906] Reference

The construction of three transcontinental lines of railway, all in successful operation, wholly within our territory, and uniting the Atlantic and the Pacific oceans, has been accompanied by results of a most interesting and impressive nature, and has created new conditions, not in the routes of commerce only, but in political geography, which powerfully affect our relations toward and necessarily increase our interests in any transisthmian route which may be opened and employed for the ends of peace and traffic, or, in other contingencies, for uses inimical to both.    From Wordnik.com.  [State of the Union Address] Reference