Usage examples (7)

• Here's the question: Just found out that lactacystin is an inhibitor of proteosome activity and may therefore be related to experimentally induced Alzheimers.
• The researchers wanted to see if they could find a molecule that inhibited Usp14, thus allowing the proteosome to work effectively.
• We have demonstrated that Nrf2 protein turnover in cells is very fast and most of Nrf2 proteins are rapidly degraded via the ubiquitin-proteosome system
• We and others have demonstrated that Keap1 functions as a substrate adaptor protein for a Cul3/Rbx1 E3 ligase complex to target Nrf2 ubiquitination and subsequent...