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{%type%} Definitions

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Short "hint"

n. - A nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid.

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Usage examples (17)
  • Ulmer settled on a method of sequencing single molecules of DNA, using an enzyme called exonuclease to nibble off bases from an unfurled DNA strand like a PacMan video game.
  • "Excision" in this case refers to excision by endonucleases or glycosylases, not nicking + exonuclease as in mismatch repair.
  • DNA polymerase, Pol I, extends the DNA from the free 3'-OH using its exonuclease activity to replace the nucleotide of the damaged base, as well as a few downstream,...
  • The idea was to attach an exonuclease to the lip of the nanopore: the enzyme would snip the end of an incoming strand of DNA like a PacMan, one base at a time.31 Each...
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