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{%type%} Definitions

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n. - Any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active.

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Usage examples (3)
  • That in the same system one can with RIA measure both an enzyme and its proenzyme and other inactive forms has both advantages and disadvantages, depending on the...
  • TPP1 is synthesized as an inactive proenzyme (pro-TPP1) that is proteolytically processed into the active enzyme after exposure to low pH in vitro or targeting to the...
  • The proenzyme structure reveals suboptimal catalytic triad geometry with its propiece linker partially blocking the substrate-binding site, which together serve to...
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