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{%type%} Definitions

WordNet 3.0Copyright Princeton University
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Short "hint"

n. - A normal gene that has the potential to become an oncogene.

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Usage examples (31)
  • How about when the final gene mutation in the proto-oncogene occurs?
  • The RET proto-oncogene in multiple endocrine neoplasia type 2 and Hirschsprung's disease.
  • Capecchi, M.R. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes.
  • The viral promoter or other transcription regulation elements in turn cause overexpression of that proto-oncogene, which in turn induces uncontrolled cellular proliferation.
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