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n. - A set of enzymes believed to snip pieces off a longer protein producing fragments of amyloid protein that bunch up and create amyloid protein plaques in brain tissue (the pathological hallmark of Alzheimer's).

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Usage examples (32)
  • The mutations affect a protein called gamma-secretase, which is involved in the build-up of protein plaques in the brains of people
  • The nicastrin protein is also a part of an enzyme called gamma-secretase, which is wedged in the cell’s membrane.
  • (Beta secretase was positively identified last year.)
  • "Even a single enzyme such as gamma secretase has an effect on 20 proteins," he said.
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